Technical Articles
Tumor Immunotherapy
Study on the Role of IL-21/IL-21R Signaling Pathway in Tumor Immunotherapy Based on TR-FRET Technology
2026-04-09IL-21 protein is one of the major immunomodulators, regulating various immune responses by influencing multiple immune cells. This protein belongs to the type I cytokine family and exhibits pleiotropic effects in tumor immunotherapy.
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- Cancer
- TR-FRET Technology
- IL-21/IL-21R
- Tumor Immunotherapy
The role and mechanism of IL-21 protein in tumor immunotherapy and its prospects for combination therapy
2026-04-02IL-21 protein belongs to the IL-2 cytokine superfamily and is primarily produced by CD4-positive T cells. It can also be partially secreted by natural killer T cells, follicular helper T cells, and CD8-positive T cells, with some lymphoid hematopoietic cells capable of producing it in small amounts.
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- Cancer
- IL-21 Protein
- Tumor Immunotherapy
- T Cells
IL-33: Can It Become the Next Target for Tumor Immunotherapy?
2025-09-16IL-33 is a member of the interleukin-1 cytokine family, initially named DVS27. It is constitutively expressed in barrier tissue cells of various organs, and its specific receptor is suppression of tumorigenicity 2 (ST2).
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- Cancer
- IL-33
- tumor immunotherapy
- Interleukin-1
- 1
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