Technical Articles

In recent years, the field of biomedicine has witnessed a technological revolution—the development of new drug research and development technologies based on protein degradation-targeting chimeras (PROTACs). PROTACs guide the ubiquitin-proteasome system (UPS) within cells to degrade specific target proteins, enabling precise regulation of disease-related proteins. This mechanism not only breaks through the limitations of traditional small-molecule drugs but also brings new hope for "undruggable" targets.