Technical Articles

VCB (VHL Complex)

Application of VCB Complex Ligand Screening Kit Based on TR-FRET Technology in Targeted Protein Degradation Research

2026-04-13

The VHL protein serves as the substrate recognition receptor of the Cullin 2 RING E3 ubiquitin ligase complex, forming the VCB complex together with Elongin B and Elongin C. This complex plays a critical role in cellular hypoxia response and protein homeostasis maintenance.

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Drug Research
TR-FRET Technology
VCB (VHL Complex)
Protein Degradation

Total 1

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