Technical Articles

IFN-γ protein is the sole member of the type II interferon family, primarily produced by activated T cells, natural killer cells, and NKT cells. This protein binds to the receptor complex composed of IFNGR1 and IFNGR2 subunits on the cell surface, activating the JAK-STAT signaling pathway and regulating the expression of multiple genes.

T细胞介导的免疫应答在抗病毒免疫中发挥核心作用。准确识别和定量分析病毒抗原特异性CD8+ T细胞是解析抗病毒免疫机制、评估疫苗效果和监测感染后免疫状态的关键技术环节。