Technical Articles

RSPO3蛋白:Wnt通路的"超级增强器",在发育、癌症与代谢中的核心枢纽
RSPO3 protein: The "super-enhancer" of the Wnt pathway, a central hub in development, cancer, and metabolism
发布时间 2025-12-05
RSPO3 (R-spondin 3) protein is a potent secreted member of the R-spondin family, serving as a core co-activator and amplifier of the Wnt/β-catenin signaling pathway, playing a decisive role in embryonic development, tissue homeostasis, and disease progression.
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  • Signaling Pathway
  • RSPO3 protein
  • R-spondin 3
  • Wnt/β-catenin signaling pathway
  • ZNRF3/RNF43
R-Spondin 1(21-146)蛋白:Wnt通路的"超级放大器",再生医学与疾病研究的革命性工具
R-Spondin 1(21-146) Protein: The "Super Amplifier" of the Wnt Pathway, A Revolutionary Tool in Regenerative Medicine and Disease Research
发布时间 2025-12-05
R-Spondin 1(21-146) is the core functional fragment of the R-Spondin 1 protein, a recombinant protein optimized through genetic engineering. It serves as a potent "catalyst" and "stabilizer" for the Wnt/β-catenin signaling pathway, playing an irreplaceable role in stem cell maintenance, tissue regeneration, and disease modeling.
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  • Signaling Pathway
  • R-Spondin 1(21-146)
  • Recombinant Protein
  • Wnt/β-catenin Signaling Pathway
  • LGR5
R-Spondin 1(21-146):Wnt通路的"超级增强器",在再生医学与疾病中的核心作用
R-Spondin 1(21-146): The "super-enhancer" of the Wnt pathway, its pivotal role in regenerative medicine and disease
发布时间 2025-11-25
R-Spondin 1(21-146) is the core active fragment of the R-Spondin 1 protein, designed to efficiently and stably amplify the Wnt signaling pathway. As a "catalyst" for tissue regeneration and stem cell maintenance, it plays a key role in intestinal health, sexual development, and disease models.
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  • Signaling Pathway
  • R-Spondin 1
  • RSPO1(21-146)
  • Wnt/β-catenin signaling pathway
  • LGR5
  • ZNRF3/RNF43
  • Organoid.
RSPO3蛋白:Wnt通路的"超级放大器"与疾病的双面关联
RSPO3 Protein: The "Super Amplifier" of the Wnt Pathway and Its Dual Association with Diseases
发布时间 2025-11-25
RSPO3 is a key member of the R-spondin protein family. As a potent secreted protein, it plays a central role in embryonic development, tissue homeostasis, and disease pathogenesis by enhancing the Wnt/β-catenin signaling pathway.
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  • Stem Cells
  • RSPO3
  • R-spondin-3
  • Wnt/β-catenin signaling pathway
  • Colorectal cancer.
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