Technical Articles

RSPO3 (R-spondin 3) protein is a potent secreted member of the R-spondin family, serving as a core co-activator and amplifier of the Wnt/β-catenin signaling pathway, playing a decisive role in embryonic development, tissue homeostasis, and disease progression.

R-Spondin 1(21-146) is the core active fragment of the R-Spondin 1 protein, designed to efficiently and stably amplify the Wnt signaling pathway. As a "catalyst" for tissue regeneration and stem cell maintenance, it plays a key role in intestinal health, sexual development, and disease models.