Technical Articles

In recent years, studies have found that abnormal expression of the anti-aging gene α - Klotho (KL) is closely associated with CKD anemia. Its high expression in the kidneys makes it a key molecule connecting kidney function and hematopoietic regulation. Although multiple clinical studies have confirmed a significant decrease in alpha Klotho levels in CKD patients with anemia, the regulatory network behind this molecular change still needs to be further elucidated.