Technical Articles

antigen-specific

LCMV MHC四聚体技术突破：驱动Immuno-STAT平台精准激活与选择性扩增抗原特异性T细胞

Breakthrough in LCMV MHC Tetramer Technology: Driving Precision Activation and Selective Expansion of Antigen-Specific T Cells via the Immuno-STAT Platform

2025-05-12

Targeted pharmacological activation of antigen-specific (AgS) T cells offers an innovative approach to overcome the limitations of current T-cell therapies. This study developed two immunotherapeutic platforms—Immuno-STAT and Neo-STAT—which achieve selective modulation of tumor-specific immune responses through the precise delivery of costimulatory ligands and peptide-HLA (pHLA) complexes to AgS T cells.

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Immunity/Inflamma
LCMV MHC tetramer technology
antigen-specific
AgS
T cell

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