Technical Articles
cell proliferation assay
KRAS Drug Screening and Bioanalytical Technology Platform—From Recombinant Proteins to Cellular Functional Assays
The development of KRAS-targeted drugs relies on a variety of biochemical and cellular analytical platforms. From the production and quality control of target proteins, to the measurement of compound binding affinity with KRAS, and the validation of signaling pathway inhibition in cells, a standardized analytical process is an essential infrastructure for new drug discovery.
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- Cancer
- Recombinant KRAS protein
- nucleotide exchange assay
- TR-FRET
- RAS-RAF binding assay
- cell proliferation assay
- efficacy evaluation model
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