Technical Articles

Cyclin-dependent kinases (CDKs), a family of serine/threonine kinases, regulate each phase of the cell cycle by forming complexes with cyclins. They are indispensable for the transition of cells from a quiescent state to a proliferative phase.

The cell cycle, encompassing the entire process from one cell division to the next, is orchestrated by cyclin-dependent kinases (CDKs), which serve as its core regulatory molecules. CDKs govern each phase of the cell cycle by forming complexes with cyclins. However, aberrant activation of CDKs is closely linked to the onset and progression of numerous cancers. In recent years, CDKs and their inhibitors have emerged as a focal area of research in cancer therapy.