Technical Articles

target protein

Lure the enemy into a trap and cut off their retreat: How RIPTAC makes tumor cells "cut off their own arm"

2026-05-28

RIPTAC (Regulated Induced Proximity Targeting Chimeras) are a class of heterobifunctional small molecules composed of three parts: one end binds to a tumor-specific target protein (Target Protein, TP), the other end binds to a ubiquitously expressed cell survival essential protein (Effector Protein, EP), and the two are connected by a chemical linker.

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Cancer
RIPTAC (Regulated Induced Proximity Targeting Chimera)
ternary complex
effector protein functional blockade
tumor-selective killing
AR
ER
effector protein
target protein

The Precision Key to Diabetes Treatment: Target Proteins Paving New Paths

2025-05-08

Diabetes, a highly prevalent metabolic disease globally, has emerged as a significant public health challenge. It is primarily classified into type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM),

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Drug Research
Diabetes
Nanjing Youai
target protein

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