Technical Articles
translational research
EPO in Translation: From Anemia Therapy to Tissue Protection and Long-Acting Formats
2026-10-15This article reviews the EPO/EPOR pathway in drug development: early recombinant erythropoietins, long-acting formats, tissue-protection directions and what these experiences teach about preclinical study design.
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- Cancer
- EPO target
- erythropoietin
- long-acting format
- tissue protection
- hypoxia
- translational research
- UA040004
M-CSF in Drug Development: The CSF1R Gateway to the Immune Microenvironment
2026-10-14CSF1R inhibitors opened macrophage-focused immunotherapy strategies. This article reviews CSF1R-directed approaches, tumor-associated macrophages and how recombinant mouse M-CSF supports translational research.
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- Immunity/Inflamma
- M-CSF
- CSF1R
- TAM
- immune microenvironment
- osteoclast
- combination therapy
- translational research
- UA040128
IL-6 in Drug Development: From Inflammation Target to Cytokine Release Syndrome
2026-10-13IL-6 blocking antibodies validated the cytokine as a drug target. This article reviews IL-6R-directed drugs, cytokine release syndrome monitoring and how recombinant mouse IL-6 supports translational research.
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- Immunity/Inflamma
- IL-6
- IL-6R
- antibody drug
- inflammation target
- cytokine release syndrome
- translational research
- UA040155
MOG (1-125) in Autoimmunity Research: From EAE Models to Translational Use
2026-10-12How recombinant MOG (1-125) underpins experimental autoimmune encephalomyelitis models and supports multiple-sclerosis and autoimmunity research workflows.
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- Immunity/Inflamma
- MOG 1-125
- EAE model
- multiple sclerosis
- autoimmunity
- translational research
- UA010471
The TSLP Turning Point from Atopic Dermatitis to Asthma: How an Epithelial Cytokine Reshapes Type 2 Inflammation Targeting
2026-10-08Once viewed as a downstream effector, TSLP is now an upstream driver target of type 2 inflammation. This article traces its narrative from epithelial alarmin to anti-TSLP therapy milestones and translational research.
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- Immunity/Inflamma
- TSLP
- type 2 inflammation
- atopic dermatitis
- asthma
- anti-TSLP monoclonal antibody
- epithelial cytokine
- translational research
- UA016092
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