Technical Articles

H-2Kd MHC四聚体揭示播散性肿瘤细胞“相对稀缺性”休眠相关免疫逃逸机制及T细胞免疫疗法的逆转作用
H-2Kd MHC Tetramer Reveals Mechanisms of Immune Evasion Related to the "Relative Rarity" Dormancy of Disseminated Tumor Cells and the Reversal Role of T Cell Immunotherapy
发布时间 2025-05-12
Though anti - tumor immune responses are activated, dormant disseminated tumor cells (DTCs) can still survive long - term. The specific mechanisms of how they escape immune surveillance remain unclear. This article introduces a study published in Cancer Cell Metabolism (IF = 50.3) in January 2025. It reveals a newly - recognized immune evasion paradigm - the "relative rarity" effect - which is the pathological basis for the persistence of DTCs.
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  • Cancer
  • H-2Kd MHC tetramer
  • tumor cells
  • DTCs
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