Technical Articles

Activin A蛋白:从关键生理调控者到疾病治疗新靶点
Activin A Protein: From Key Physiological Regulator to Novel Therapeutic Target
发布时间 2025-11-19
Activin A, a key member of the TGF-β superfamily, is a dimeric protein formed by two βA subunits linked via disulfide bonds. This critical signaling molecule plays a central role in physiological processes such as embryonic development, tissue repair, and immune regulation, but its dysregulation has also become a pivotal factor in the pathogenesis of various diseases.
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  • Cancer
  • Activin A protein
  • TGF-β superfamily
  • fibrotic diseases
  • tumor progression
  • muscle atrophy
Activin A:一把调控生命进程的双刃剑
Activin A: A Double-Edged Sword in Regulating Life Processes
发布时间 2025-11-19
Activin A is a secreted protein belonging to the transforming growth factor-β superfamily. Like other well-known family members such as TGF-β and BMPs, it plays a central role in cell growth, differentiation, and apoptosis.
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  • Cancer
  • Activin A protein
  • TGF-β superfamily
  • fibrotic diseases
  • tumor progression
  • muscle atrophy
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