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The colony-stimulating factor (CSF) superfamily is associated with mammalian myelopoiesis, including the development of monocytes, macrophages, dendritic cells (DCs), and polymorphonuclear macrophages. This family comprises three major members: M-CSF (macrophage colony-stimulating factor), G-CSF (granulocyte colony-stimulating factor), and GM-CSF (granulocyte-macrophage colony-stimulating factor).