Product Application

The transformation of normal cells into cancer cells is accompanied by progressive changes in multiple molecules, which often lead to abnormal expression of specific genes and disruption of tissue homeostasis. These changes include: activation of proliferative signaling, resistance to apoptosis, unlimited replicative potential, immune evasion, and ultimately activation of invasion and metastasis pathways, resulting in uncontrolled tumor growth and proliferation. Simultaneously, these changes facilitate the generation of genetically heterogeneous cells within the same tumor microenvironment, posing challenges for tumor diagnosis and treatment. Several key cell surface proteins that mediate cell signaling, adhesion, and immune evasion are frequently exploited by tumor cells to promote their own growth and proliferation.