Product Application

Helper T cell 2 (Th2) is a crucial functional subset of CD4⁺ T cells, playing a central role in humoral immune responses, allergic reactions, and anti-parasitic infections. Naive CD4⁺ T cells (Th0) can differentiate into Th2 cells under the guidance of specific cytokine signals, a process known as "Th2 polarization." Whether studying allergic diseases such as asthma and atopic dermatitis, exploring anti-parasitic immune mechanisms, or developing novel immunotherapies, mastering in vitro Th2 cell polarization techniques is essential.

U-Ai Biotech proudly introduces the Human Monocyte-Induced Osteoclast Differentiation Cytokine Kit, meticulously equipped with the two core factors M-CSF and RANKL. Featuring standardized ratios and high activity, it ensures accelerated and efficient osteoclast induction!

In immunology, research on inflammatory mechanisms, and drug screening, the functional state of macrophages is one of the key research focuses. The human THP-1 cell line, due to its stable origin and consistent genetic background, is widely used in vitro studies of monocyte-macrophage polarization. However, how to efficiently and stably induce THP-1 cells into M1-type (classically activated) or M2-type (alternatively activated) macrophages remains critical for experimental success.

Osteoclasts (OCs) are the only multinucleated giant cells in bone tissue capable of bone resorption, and their abnormal differentiation and function are closely associated with various diseases such as osteoporosis, rheumatoid arthritis, and bone tumors. Establishing a stable and efficient in vitro induction model for osteoclast differentiation is fundamental to bone metabolism research.

In tumor immunology, vaccine development, and autoimmune disease research, the importance of dendritic cells (DCs) as the "immune commanders" is self-evident.

During pregnancy, the harmonious coexistence between mother and fetus is the key to maintaining a healthy pregnancy. However, there is a disease that often breaks this balance and poses a serious threat to pregnant women and fetuses, and that is preeclampsia (PE).

Wnt protein is an important class of signaling molecules that play an indispensable role in cell growth, differentiation, migration and tissue homeostasis maintenance.

the palmitoylation of TEAD proteins is a very important regulatory mechanism in cells. It not only affects the normal function of the Hippo pathway, but also has a close relationship with the occurrence of cancer.

Chimeric Antigen Receptor T-Cell (CAR-T) therapy represents a revolutionary approach in cancer treatment, involving the engineering of a patient's own T cells to recognize and attack cancer cells. Although CAR-T therapy has demonstrated remarkable efficacy in treating certain hematologic malignancies, its application in solid tumors remains fraught with numerous challenges. Cytokines play a pivotal role in the expansion, survival, and functional modulation of CAR-T cells.

Colony-Stimulating Factors (CSFs) are a class of proteins that play a crucial role in biological systems. Their primary function is to stimulate and regulate the proliferation and differentiation of hematopoietic progenitor cells, thereby contributing to the process of hematopoiesis.