Recombinant Human CD40 Fc Chimera: How the Immune Switch Is Opened at the Molecular Level
CD40 is a TNF receptor family costimulatory molecule on B cells and dendritic cells. This article explains its trimerization-driven signaling, CD40L engagement and why the Fc chimera format is the standard reagent for binding studies.
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Abstract: CD40 is a TNF receptor family costimulatory molecule on B cells and dendritic cells. This article explains its trimerization-driven signaling, CD40L engagement and why the Fc chimera format is the standard reagent for binding studies.
Keywords: CD40, TNFRSF5, CD40L, Fc chimera, costimulation, B cell, dendritic cell, TRAF, UA010194
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
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