High-Throughput AMP-Related Enzyme Target Drug Screening Technology UA-Glo® AMP Assay Kit

High-Throughput AMP-Related Enzyme Target Drug Screening Technology UA-Glo® AMP Assay Kit

  • Recent Advances
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Recent Advances

Applications:

 

  • AMP or related enzyme activity detection

  • Inhibitor screening

  • Quantification of inhibitor potency (IC50)

 

Detection Principle:


 

Detection Range & Hot Targets:

 

  • cAMP-specific phosphodiesterase (cAMP-PDE)

  • ADP-ribosyl hydrolase (ADPRH)

  • Extracellular adenosine metabolic enzyme (ENPP1)

  • CD73 & CD39

  • Post-translational modification-related enzymes: Ubiquitination, SUMOylation, NEDDylation

  • Aminoacyl-tRNA synthetases (aaRSs)

  • DNA ligase

  • Ribonucleases (e.g., Poly(A) Deadenylases)

 

Advantages:

 

  • Suitable for detecting low-activity enzymes

  • Ideal for high-throughput enzyme or inhibitor screening

  • High sensitivity and broad linear dynamic range

  • Extremely low false-positive rate

  • Chemiluminescence-based detection, unaffected by fluorescent compounds

  • Simple workflow: Mix-Add-Detect

 

Related Products:

 

货号

品名

规格

UA079024

UA-Glo® AMP Assay Kit

1,000assays/10,000assays

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