New Product Launch|Human Monocyte-Induced Osteoclast Differentiation Cytokine Kit, Efficient Osteoclast Induction!

U-Ai Biotech proudly introduces the Human Monocyte-Induced Osteoclast Differentiation Cytokine Kit, meticulously equipped with the two core factors M-CSF and RANKL. Featuring standardized ratios and high activity, it ensures accelerated and efficient osteoclast induction!

  • Recent Advances
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Recent Advances

UA BIOSCIENCE proudly presents the Human Monocyte-Induced Osteoclast Differentiation Cytokine Kit, precisely equipped with two core factors—M-CSF and RANKL. With standardized ratios and high bioactivity, it accelerates efficient osteoclast induction!


Product Specifications

Catalog No. Specification Components
UA090058 S Size (100ml System) CSF Protein, Human; RANK L/TNFSF11 (178aa) Protein, Human
UA090058 M Size (1000ml System)

Product Information

The process of osteoclast formation regulated by M-CSF and RANKL


Product Advantages

1. No need for self-preparation

M-CSF (UA040042) and RANKL (UA040329) are precisely matched, eliminating the need for manual combination.

2. Validated combination, no need for optimization

The recommended optimal induction concentrations are 50ng/mL M-CSF + 100ng/mL RANKL, eliminating the need for repeated optimization.

3. Detailed protocol with clear dosages

Includes complete steps for sorting, induction, and identification, with clear procedures and dosages, avoiding complex optimization.

4. High purity, high activity, cost-effective, low endotoxin

High protein purity and bioactivity, endotoxin content <0.1EU/μg.


Activity Data

After 6 days of RANKL induction, classic multinucleated osteoclast structures can be observed under the microscope.

After 6 days of RANKL induction, Tartrate-Resistant Acid Phosphatase (TRAP) staining is performed to specifically identify osteoclasts. After staining, mature osteoclasts exhibit red or purple-red cytoplasm under optical microscopy.


This induction system has been widely used in studies on osteoclast differentiation mechanisms, bone remodeling regulation, pathological mechanisms of bone metabolic diseases, and high-throughput screening of anti-bone resorption drugs, providing high-quality products and technical support for clinical diagnosis and treatment of bone-related diseases.

For more cytokine-related products and kits, welcome to contact UA BIOSCIENCE~

This article is reviewed and published by the technical expert team of UA

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