Structural Characterization: Your “Strength” Is Here (U&I Enzyme Edition)!
1. Glycosidase Family: PNGase F: This “glycan scissor” can easily remove high mannose, hybrid, and complex oligosaccharides from N-glycoproteins, making your glycan analysis a breeze! Endo S: Specializing in the glycosylation patterns of IgG, it helps you uncover the mysteries of antibodies. Endo H: The “specific cutter” for high mannose-type glycan chains, making your glycan analysis more precise. Endo S2: A “glycan structure decoder” that helps you study the impact of glycans on protein function.
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Hey guys!
Today, I want to introduce a series of super powerful enzymatic tools. These are not ordinary tools; they are the “Swiss Army knives” in the world of biological macromolecule structural characterization!
U&I Protein's Enzymatic Toolbox
Hey guys, are you struggling with the complex glycosylation modifications and antibody structures when studying the structure and function of proteins and glycoproteins? Don't worry, U&I Protein is here to save your research day!
1. Glycosidase Family:
PNGase F: This “glycan scissor” can easily remove high mannose, hybrid, and complex oligosaccharides from N-glycoproteins, making your glycan analysis a breeze!
Endo S: Specializing in the glycosylation patterns of IgG, it helps you uncover the mysteries of antibodies.
Endo H: The “specific cutter” for high mannose-type glycan chains, making your glycan analysis more precise.
Endo S2: A “glycan structure decoder” that helps you study the impact of glycans on protein function.
2. Protease Family:
IdeS: The “little master” of IgG degradation, it hydrolyzes IgG into F(ab')₂ fragments and Fc fragments, essential for antibody drug preparation and characterization!
IdeZ: Just as powerful as IdeS, it helps you prepare antibodies or antibody Fc fragments containing only the F(ab')₂ fragment.
Endoproteinase Glu-C: The “cutting expert” of serine proteases, targeting the carboxyl side of aspartate and glutamate residues, it is crucial for protein sequence analysis!
Endoproteinase Asp-N: The “cleavage master” of metalloproteases, it performs exceptionally in protein digestion and peptide analysis.
3. Specialty Enzymatic Products:
M-bovin-GalT1(Y289L): A mutated galactosyltransferase, it is a “reliable assistant” for glycan synthesis and glycoprotein engineering.
Hey guys, these enzymatic products are like your research assistants, helping you easily solve the puzzles of biological macromolecule structural characterization. Whether it's basic research or drug development, they can show their prowess!
Come and follow U&I Protein, we have more treasure products waiting for you to discover!
Hey guys, if you are interested in these enzymatic products or want to know more, feel free to leave a message and consult us anytime! We are here waiting for you!
This article is reviewed and published by the technical expert team of UA
Disclaimer: This article partially utilizes artificial intelligence assistance in its creation. If any content involves copyright or intellectual property issues, please let us know and we promise to verify and remove it as soon as possible.
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