IL-18BP Fc Chimera Protein, Human

2μg (R: reducing conditions, N: non-reducing conditions).

Measured by its binding ability in a functional ELISA. When Recombinant Human IL-18 is immobilized 2.5µg/mL (100µl/well), Recombinant Human IL-18BP Fc Chimera binds with an EC50 of 0.07-0.1μg/ml.

Immobilized IL-18, Human (Cat. No. UA040111) at 2.0μg/mL (100μL/well) can bind IL-18BP Fc Chimera, Human (Cat. No. UA010587) with EC50 of 2.20-3.25ng/ml.

Protein A Chip captured IL-18BP Fc Chimera, Human (Cat. No. UA010587), can bind IL-18, Human(Cat. No. UA040111) with an affinity constant of 75.59pM as determined in SPR assay.