H-2K(d)/IYSTVASSL Influenza HA Tetramer-PE: A Precision Tool for Virus-Specific CD8+ T Cell Research
The MHC H-2K(d)/IYSTVASSL Influenza HA Tetramer-PE is a high-sensitivity reagent specifically designed for detecting influenza virus-specific CD8+ T cells. Utilizing optimized tetramer technology, this product enables precise identification of T cells targeting the influenza virus hemagglutinin antigen in BALB/c (H-2d) mouse models, providing a reliable solution for infectious immunology research.
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Product Overview
MHC H-2K(d)/IYSTVASSL Influenza HA Tetramer-PE is a high-sensitivity reagent specifically designed for detecting influenza virus-specific CD8+ T cells. Utilizing optimized tetramer technology, this product enables precise identification of T cells targeting the hemagglutinin antigen of influenza virus in BALB/c (H-2d) mouse models, providing a reliable solution for infectious immunology research.
Key Advantages
Precise Specificity: Strictly matches H-2K(d) allele, specifically recognizing influenza HA antigen epitope
Outstanding Sensitivity: PE labeling provides ultra-high signal-to-noise ratio, enabling detection of low-frequency T cell populations
Reliable Stability: Stable tetramer structure ensures reproducible experimental results
Ready-to-Use Design: Optimized formulation for easy operation, saving experimental time
Technical Features
Molecular Characteristics
MHC Restriction: H-2K(d) allele
Antigen Peptide: Immunodominant epitope of influenza virus hemagglutinin (IYSTVASSL)
Fluorescent Label: High-purity PE, excitation wavelength 565nm, emission wavelength 575nm
Quality Assurance
Rigorous quality control process
Batch-to-batch consistency guarantee
Detailed quality control certificate provided
Main Applications
Viral Infection Research
Dynamic monitoring of T cell responses in influenza virus infection models
Detection of virus-specific T cells in lung tissue and draining lymph nodes
Study of T cell kinetics during acute infection and memory phases
Vaccine Evaluation
Assessment of influenza vaccine immunogenicity
Quantitative analysis of CD8+ T cell responses induced by vaccines
Evaluation of novel vaccine platforms
Immunological Mechanism Research
Exploration of T cell memory formation mechanisms
Analysis of tissue-resident memory T cell characteristics
Study of T cell exhaustion and functional states
Experimental Support
Standardized Protocols
Recommended staining concentration: 0.5-2 μg/10^6 cells
Optimal staining conditions: 30 minutes at room temperature, protected from light
Compatible with multicolor flow cytometry
Professional Technical Support
Detailed experimental protocols and troubleshooting guides
Personalized multicolor panel design advice
Comprehensive support from technical team
Technical Specifications
Storage Conditions: 2-8°C, protected from light
Specification: 50 tests
Purity: >95%
Applicable Species: Mouse (BALB/c background)
Detection Method: Flow cytometry
Frequently Asked Questions
| Question | Answer |
|---|---|
| Q: Is this tetramer suitable for other mouse strains? | A: Only applicable to H-2d haplotype mice, including BALB/c, DBA/2, etc. |
| Q: How to set up experimental controls? | A: Uninfected mouse samples are recommended as negative controls, and irrelevant peptide tetramers may be used when necessary. |
| Q: What is the detection sensitivity? | A: Under optimized conditions, antigen-specific T cells with frequencies as low as 0.01% can be detected. |
Why Choose Us
Professional Quality: Strict quality control system
Excellent Performance: High sensitivity and specificity
Comprehensive Support: Professional technical service team
Rich Experience: Years of experience in immunology research reagent development
UA-MHC H-2K(d)/IYSTVASSL Influenza HA Tetramer-PE Labelled_UA089052_UA BIOSCIENCE Official Website
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